Creatine Supplementation And Brain Health
There is a robust and compelling body of evidence supporting the ergogenic and therapeutic role of creatine supplementation in muscle. Creatine Supplementation And Brain Health
Beyond these well-described effects and mechanisms, there is literature to suggest that creatine may also be beneficial to brain health (e.g., cognitive processing, brain function, and recovery from trauma).
There is a potential for creatine supplementation to improve cognitive processing, especially in conditions characterized by brain creatine deficits, which could be induced by acute stressors (e.g., exercise, sleep deprivation) or chronic, pathologic conditions (e.g., creatine synthesis enzyme deficiencies, mild traumatic brain injury, aging, Alzheimer’s disease, depression).
Despite this, the optimal creatine protocol able to increase brain creatine levels is still to be determined. Similarly, supplementation studies concomitantly assessing brain creatine and cognitive function are needed. Collectively, data available are promising and future research in the area is warranted.
Can Supplementing With Creatine Support Your Brain?
Creatine is perhaps the most well-known and well-researched nutritional supplement in the sports performance world. Creatine is beloved by gym rats for its safety and efficacy in supporting the body’s energy needs during exercise and its role in promoting muscle health.*
However, as we further understand brain function and cognitive performance, research is looking at creatine as a possible way to support the brain in some of the same ways creatine has proven to sustain the body during training and injury.
Creatine 101
Common Uses
Creatine is most commonly used as an athletic performance enhancer. It appears creatine has the ability to increase strength and improve lean body mass during high-intensity, short-duration workouts such as weightlifting or sprinting. Creatine may also be effective in treating heart disease. According to the University of Maryland Medical Center, creatine improves low levels of energy, can help lower triglycerides and can lower levels of homocysteine, which is a precursor to having a heart attack or stroke. In addition, creatine has been used to treat depression, bipolar disorder, Parkinson’s disease, Lou Gehrig’s disease, arthritis, an eye disease known as gyrate atrophy, McArdle’s disease and muscular dystrophy.
Creatine is an amino acid that is necessary for creating ATP, the body’s on demand source of energy. Although some creatine is generated in our liver and kidneys, we don’t make enough to fill our tanks.
Creatine is found naturally only in animal products, and it’s susceptible to degradation during cooking processes. Although numbers vary due to the quality of food source, genetics, and demands on the body, it is estimated that the majority of us get a little more than two-thirds of what we need from what we produce and what we eat. And following a plant-based or vegan diet, above-average exercising, highly stimulating activities, and injury, all increase our need for creatine.
Unlike creatine in foods, creatine monohydrate in supplement form is not damaged by cooking and has been shown in hundreds of studies to improve creatine stores in the body. About 95% of creatine is stored in muscle, with the remaining 5% being found in high energy organs like the brain.1
Creatine supports energy function in two ways. First, to create energy we break down a three-phosphate compound (ATP) to a two-phosphate compound (ADP). To then restart the energy cycle, we must find an extra phosphate to recycle ADP into ATP; this is where creatine comes in.
As creatine intake increases, we stockpile phosphocreatine, a combination of creatine and phosphate, in our muscles and brains. In our energy system, phosphocreatine donates its phosphate to ADP and the process starts over again. A second, more indirect pathway runs through the mitochondria, the powerhouse of our cells.
Phosphocreatine plays a significant role in the process that delivers energy from the mitochondria to other parts of the cell that need energy. The more efficient this pathway is, the less stress is put on the mitochondria.
Creatine And The Brain
After our muscles, the brain is among the highest consumers of energy in the body; and while muscles can rest, the brain runs 24/7. Although the brain takes up only 2% of our body weight, it uses 20% of our calorie intake. When we ask our brain to think and process more, or function under suboptimal conditions, we can see the same performance and recovery issues as muscles when proper nutrients aren’t provided.
In areas where the brain’s performance involves a heavy cognitive load, such as driving a racecar or competing in esports, or in situations where lack of sleep or oxygen occurs, planning to support the brain plays a crucial role in maintaining its optimal function.
Adequate creatine stores in the brain allow for optimal energy production to support brain health and cognitive performance, similar to creatine’s long-studied positive impact on muscle energy and physical performance.* As we age, creatine stores tend to decrease in our muscles and our brains, likely due to disease or decreased physical activity.
Just like we see the benefits of creatine supplementation in skeletal muscle, we are starting to see the potential for similar impacts on the brain.* When brain creatine levels in healthy elderly participants were compared to a younger cohort, they were similar, which has led to new areas of research to better understand what this correlation means.
Creatine And Dehydration
A well-known effect of creatine supplementation is muscle hydration, which involves the retention of body water in your skeletal muscles along with creatine. Muscle hydration may leave less water available for the rest of your body’s cells to function optimally, causing a state of dehydration. Dehydration, or a lack of water, can affect your brain by reducing blood flow and oxygen delivery to brain cells. This may cause you to feel faint or lightheaded and can increase your risk of developing acute anxiety, nervousness and confusion.
Emerging Research
Although the link between creatine and physical performance has been studied for decades, creatine’s link to the brain is only an emerging area of investigation. Studies show that supplemental creatine monohydrate over 2-4 weeks increases the concentration of creatine in the brain by 5-15%.3,4
The brain is more selective about what chemicals and nutrients it allows in than are the muscles, so we can’t assume that existing creatine loading protocols can be applied to supporting cognitive performance. The emerging theory is that larger doses will be needed over a longer term to promote optimal creatine levels in the brain.5
Although studying creatine’s impact on the brain is more complex than muscle-based studies, one group has made it easier to tease out significant benefits – vegans/vegetarians. As noted earlier, creatine isn’t present in diets that eliminate animal products, leading this group to have a smaller creatine pool than the average population.
Healthy vegan and vegetarian participants that supplemented with creatine performed better than placebo groups on a series of cognitive challenges, including word recall, repeating numbers backward, pattern recognition, and reaction time.*6-8
Although research has shown that cognitive training by itself can lead to higher brain creatine levels absent supplementation,9 creatine supplementation has shown positive benefits as well.* For example, creatine can decrease the impact of fatigue when performing complex tasks after sleep deprivation.* It has also been shown to improve throwing accuracy in rugby athletes.*10-12
When participants were deprived of oxygen to the brain, mimicking emergency conditions, individuals who had supplemented with creatine for one week restored cognitive performance more readily than the placebo group,* indicating that creatine plays an important role in providing energy to brain cells when usual energy sources are jeopardized.13
When examining the impact of creatine supplementation on brain fog, students who supplemented with creatine for five days prior to a math test were found to have more oxygen in brain cells.* This is likely due to an increase in oxygen uptake from the blood and mitochondria efficiency resulting in a decreased need for oxygen.14
Changes in the brain after injury include membrane disruption, mitochondrial damage, and increased oxidative stress – all things creatine is known to support elsewhere in the body.*
While it is too early in the research to make any definitive connection between creatine supplementation and brain function, further investigating the potential remains a priority in the research community.
Creatine supplementation probably would provide the most benefit for individuals with suboptimal levels.15 Further research is needed to solidify dosing strategies and to control for variables, including age, diet, activity, and genetic makeup. It will likely continue to be an area of intense interest across the medical, cognitive, and sports performance communities.
Creatine From Meat Seems To Help Us Think
Are you a vegetarian or a vegan? Besides vitamin B12, depending upon what you eat and the supplements you take, you can find your diet somewhat low in zinc, long chain omega 3 fatty acids, and even some amino acids. One of these amino acids is called creatine, and the best source is meat.
Researchers who study cognition and athletic performance simply love giving vegetarians creatine supplements (1)(2)(3). This practice might seem curious until you look at the following facts:
1) Creatine is an amino acid found only in animal flesh but most abundantly in skeletal muscle flesh (like steak). It is not an essential amino acid, as we can synthesize is from other amino acids found also in plant foods, but as with changing the plant-based omega 3 fatty acid ALA to the marine animal based omega 3 acid DHA, the synthesis is inefficient. It is known that vegetarians have lower tissue (measured directly via muscle biopsy) amounts of creatine than omnivores (4).
2) Why should we care if we have creatine? Well, if you recall, our cells run on energy supplied by a molecule called ATP. Think of ATP as the gasoline of the body. Whether we fuel up with glucose or ketones, eventually those raw materials get transformed into ATP, which as it is broken down powers all sorts of energy-requiring processes. We will obviously burn through ATP faster in our muscles when we are running or jumping or performing various feats of strength, but we also burn through ATP faster when we are using our noggins for something a bit complicated. Our little brain (the size of your two fists held together) burns through 20 percent of the energy we use each day, primarily to keep those ion gradients fueled that allow our neurons to charge up and then be discharged to communicate information.
3) Creatine can bind to phosphate (P) to make phosphocreatine, and this acts as a “buffer” to make ATP lickety-split. Turns out we can make ATP 12 times faster using phosphate reserves from phosphocreatine than by using the standard method of oxidative phosphorylation and a whopping 70 times faster than making ATP de novo. When we think hard, brain levels of phosphocreatine can drop pretty acutely while ATP levels stay constant, showing that we can bust into that reserve to keep our thinking sharp. In short, creatine improves brain efficiency. It is the “turbo boost” of the brain and muscles.
So let’s look at these papers, shall we? In both the cognition study papers, healthy college students were recruited (colleges being both a good source of research volunteers and vegetarians) and divided into creatine or placebo supplementation groups. The British study compared vegetarians and vegan young women to omnivores, the Australian study used only vegetarians and vegans, but had a crossover design (all subjects got both placebo and creatine along the way). Both studies did various measures of cognitive and memory testing (number of words you can remember from a list read to you, how many F or P words you can say in two minutes, how many numbers you can repeat backwards from a string of numbers read to you, recognizing strings of three even or odd numbers in a series of numbers read at 100 per second). The British study added a measure of reaction time (subjects had to press a button corresponding to a light as fast as they could once it was lit). The Australian study was six weeks, the British study was five days, and both used 5g creatine monohydrate as the supplement and dextrose (glucose) as the control.
Because glucose administration has been shown to (immediately) increase cognitive performance (5), all the cognitive testing was done fasted and on a day with no supplementation.
The results? First off, everyone, vegetarian or omnivore, on placebo or creatine in the British study did worse the second time around on the memory tests (maybe they got bored?). But compared to the placebo group, the omnivores in the British study were about the same as the creatine supplement group (omnivores have been shown to benefit from a maximum of 20 grams a day at first then maintenance 2-5 grams per day supplementing for athletic performance), suggesting that us animal flesh eaters have a physiologically appropriate amount of phophocreatine reserve in the brain for interesting tasks such as pushing buttons in response to light stimuli and complicated mental tasks that involve the prefrontal cortex and the hippocampus.
The vegetarians in the creatine group did much better than the vegetarians in the placebo group on the second battery of tests involving word recall and measures of variability of reaction times. More simple mental tasks didn’t improve in the vegetarians or the omnivores, suggesting, interestingly enough, that complicated thinking burns more energy than uncomplicated thinking (so do smart people burn more calories? I’m not aware of any research to that effect, in fact I thought there wasn’t much of a difference, but we’ll look into it …). In some of the measures, vegetarians were higher than omnivores at baseline, by the way, and in general the memory tests between the two groups did not vary at baseline—the vegetarians just seemed to benefit much more from creatine supplementation.
In the Australian study (using only vegans and vegetarians), creatine supplementation had a significant positive effect on working memory (using backwards digit span) and intelligence measures requiring processing speed. Various cognitive tasks that were worse in the placebo vegetarians compared to creatine vegetarians are similar to those that are affected in ADHD, schizophrenia, dementia, and traumatic brain injury. In addition, people with the Apoe4 allele and therefore more vulnerable to developing Alzheimer’s seem to have lower brain levels of creatine.
Except there are a few wee wrinkles. It turns out that creatine supplementation seems to have an effect on glucose regulation (3)(6). Weirdly, the first study shows a higher glucose level to oral glucose tolerance load (in vegetarians), and the second study (in young athletically active males) shows a lower amount of area under the oral glucose tolerance test curve (that’s good—shows increased glycemic control) with creatine supplementation. But if we consider the fact that a ready supply of glucose in the short term can improve cognitive performance, the British investigators were wondering if creatine supplementation increased glucose in vegetarians, thus increasing cognitive performance. They didn’t bother to measure the glucose in the subjects, though, so who knows. In the Australian study, glucose was measured in the fasting subjects but specific levels were not reported in the paper, but it didn’t seem that anyone had a high level.
In addition, creatine in the tissue doesn’t necessarily equal creatine in the brain. Animal studies have shown that problems with the creatine transporter into the brain shows up as cognitive problems similar to the unsupplemented human vegetarians (compared to their supplemented vegetarian brethren). However, it is likely that the synthesis and transport mechanisms are upregulated in vegetarians (as they have low levels of creatine), so creatine might pack more punch early on for the veggies, until levels become saturated.
Well, I’m not all that interested in supplementing with creatine. But I am interested in continuing to eat steak, and in having the most efficient energy reserves available for my brain. Eating a bit of meat along the way seems like a reasonable way to achieve this goal.
Conflict Of Interest Statement
B.G. has received research grants, creatine donation for scientific studies, travel support for participation in scientific conferences and honorarium for speaking at lectures from AlzChem (a company which manufactures creatine). Additionally, he serves as a member of the Scientific Advisory Board for Alzchem. E.S.R. has conducted industry-sponsored research on creatine and received financial support for presenting on creatine at industry-sponsored scientific conferences. Additionally, he serves as a member of the Scientific Advisory Board for AlzChem, who sponsored this special issue. S.M.O. serves as a member of the Scientific Advisory Board on creatine in health and medicine (AlzChem LLC). S.M.O. owns patent “Sports Supplements Based on Liquid Creatine” at the European Patent Office (WO2019150323 A1), and active patent application “Synergistic Creatine” at the UK Intellectual Property Office (GB2012773.4). S.M.O. has served as a speaker at Abbott Nutrition, a consultant of Allied Beverages Adriatic and IMLEK, and an advisory board member for the University of Novi Sad School of Medicine, and has received research funding related to creatine from the Serbian Ministry of Education, Science, and Technological Development, Provincial Secretariat for Higher Education and Scientific Research, AlzChem GmbH, KW Pfannenschmidt GmbH, and ThermoLife International LLC. S.M.O. is an employee of the University of Novi Sad and does not own stocks and shares in any organization.
References
- Andres R, Ducray A, Schlattner U, et al. Functions and effects of creatine in the central nervous system. Brain Res Bull 2008;76(4):329-343.
- Solis M, Artioli G, Otaduy M, et al. Effect of age, diet, and tissue type on PCr response to creatine supplementation. J Appl Physiol 2017;123(2):407-414.
- Dechent P, Pouwels P, Wilken B, et al. Increase of total creatine in human brain after oral supplementation of creatine-monohydrate. Am J Physiol 1999;277(3):R698-R704.
- Lyoo I, Kong S, Sung S, et al. Multinuclear magnetic resonance spectroscopy of high-energy phosphate metabolites in human brain following oral supplementation of creatine-monohydrate. Psychiatry Res 2003;123(2):87-100.
- Dolan E, Gualano B, Rawson E. Beyond muscle: the effects of creatine supplementation on brain creatine [and] cognitive processing . . . . EJSS 2019;19(1):1-14.
- Benton D, Donohoe R. The influence of creatine supplementation on the cognitive functioning of vegetarians and omnivores. Br J Nutr 2011;105(7):1100-1105.
- Rae C, Digney A, McEwan S, Bates T. Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial. Proc Biol Sci 2003;270(1529):2147-2150.
- Ferrier C, Alarcón G, Glover A, et al. N-Acetylaspartate and creatine levels measured by (1)H MRS relate to recognition memory. Neurology 2000;55(12):1874-1883.
- Valenzuela M, Jones M, Wen W, et al. Memory training alters hippocampal neurochemistry in healthy elderly. Neuroreport 2003;14(10):1333-1337.
- Cook C, Crewther B, Kilduff L, et al. Skill execution and sleep deprivation: effects of acute caffeine or creatine supplementation. A randomized placebo-controlled trial. J Int Soc Sports Nutr 2011;8:2.
- McMorris T, Harris R, Swain J, et al. Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol. Psychopharmacology 2006;185(1):93-103.
- McMorris T, Harris R, Howard A, et al. Creatine supplementation, sleep deprivation, cortisol, melatonin and behavior. Physiol Behav 2007;90(1):21-28.
- Turner C, Byblow W, Gant N. Creatine supplementation enhances corticomotor excitability and cognitive performance during oxygen deprivation. J Neurosci 2015;35(4):1773-1780.
- Watanabe A, Kato N, Kato T. Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation. Neurosci Res 2002;42(4):279-285.
- Avgerinos K, Spyrou N, Bougioukas K, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol 2018;108:166-173.
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Ultimate Resource For Leading Non-Profits Focused On Policy Issues Facing Cryptocurrencies
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Financial Advisers Are Betting On Bitcoin As A Hedge
ECB President Christine Lagarde (French Convict) Says, Bitcoin Enables “Funny Business.”
German Police Shut Down Darknet Marketplace That Traded Bitcoin
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Broker Touts Exotic Bitcoin Bet To Squeeze Income From Crypto
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Bitcoin’s Bulls Should Fear Its Other Scarcity Problem
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Bitcoin Looks To Gain Traction In Payments
BTC Market Cap Now Over Half A Trillion Dollars. Major Weekly Candle Closed!!
Elon Musk And Satoshi Nakamoto Making Millionaires At Record Pace
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Santoshi Nakamoto Delivers $24.5K Christmas Gift With Another New All-Time High
Bitcoin’s Rally Has Already Outlasted 2017’s Epic Run
Gifting Crypto To Loved Ones This Holiday? Educate Them First
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HTC Smartphone Will Run A Full Bitcoin Node (#GotBitcoin?)
HTC’s New 5G Router Can Host A Full Bitcoin Node
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Andreas M. Antonopoulos And Simon Dixon Say Don’t Buy Bitcoin!
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Bitcoin Moves $500K Around The Globe Every Second, Says Samson Mow
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Bitcoin Is The Tulipmania That Refuses To Die
Ultimate Resource On Ethereum 2.0
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Bitcoin Is Winning The Monetary Revolution
Cash Is Trash, Dump Gold, Buy Bitcoin!
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World’s First 24/7 Crypto Call-In Station!!!
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Ultimate Resource On Mike Novogratz And Galaxy Digital’s Bitcoin News
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3 Reasons Why Bitcoin Price Suddenly Dropping Below $13,000 Isn’t Bearish
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PayPal To Offer Crypto Payments Starting In 2021 (A-Z) (#GotBitcoin?)
As Bitcoin Approaches $13,000 It Breaks Correlation With Equities
Crypto M&A Surges Past 2019 Total As Rest of World Eclipses U.S. (#GotBitcoin?)
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Mad Money’s Jim Cramer Will Invest 1% Of Net Worth In Bitcoin Says, “Gold Is Dangerous”
State-by-state Licensing For Crypto And Payments Firms In The Us Just Got Much Easier (#GotBitcoin?)
Bitcoin (BTC) Ranks As World 6Th Largest Currency
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Ultimate Resource On Non-Fungible Tokens
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An Israeli Blockchain Startup Claims It’s Invented An ‘Undo’ Button For BTC Transactions
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US Appeals Court Allows Warrantless Search of Blockchain, Exchange Data
Central Bank Rate Cuts Mean ‘World Has Gone Zimbabwe’
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China Discovers 4% Of Its Reserves Or 83 Tons Of It’s Gold Bars Are Fake (#GotBitcoin?)
Former Legg Mason Star Bill Miller And Bloomberg Are Optimistic About Bitcoin’s Future
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Australia Post Office Now Lets Customers Buy Bitcoin At Over 3,500 Outlets
Anomaly On Bitcoin Sidechain Results In Brief Security Lapse
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Activists Document Police Misconduct Using Decentralized Protocol (#GotBitcoin?)
Supposedly, PayPal, Venmo To Roll Out Crypto Buying And Selling (#GotBitcoin?)
Industry Leaders Launch PayID, The Universal ID For Payments (#GotBitcoin?)
Crypto Quant Fund Debuts With $23M In Assets, $2.3B In Trades (#GotBitcoin?)
The Queens Politician Who Wants To Give New Yorkers Their Own Crypto
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US Drug Agency Failed To Properly Supervise Agent Who Stole $700,000 In Bitcoin In 2015
Layer 2 Will Make Bitcoin As Easy To Use As The Dollar, Says Kraken CEO
Bootstrapping Mobile Mesh Networks With Bitcoin Lightning
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BitPay’s Prepaid Mastercard Launches In US to Make Crypto Accessible (#GotBitcoin?)
Germany’s Deutsche Borse Exchange To List New Bitcoin Exchange-Traded Product
‘Bitcoin Billionaires’ Movie To Tell Winklevoss Bros’ Crypto Story
US Pentagon Created A War Game To Fight The Establishment With BTC (#GotBitcoin?)
JPMorgan Provides Banking Services To Crypto Exchanges Coinbase And Gemini (#GotBitcoin?)
Bitcoin Advocates Cry Foul As US Fed Buying ETFs For The First Time
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Meet Brian Klein, Crypto’s Own ‘High-Stakes’ Trial Attorney (#GotBitcoin?)
3 Reasons For The Bitcoin Price ‘Halving Dump’ From $10K To $8.1K
Bitcoin Outlives And Outlasts Naysayers And First Website That Declared It Dead Back In 2010
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Antonopoulos: Chainalysis Is Helping World’s Worst Dictators & Regimes (#GotBitcoin?)
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Iran Ditches The Rial Amid Hyperinflation As Localbitcoins Seem To Trade Near $35K
Buffett ‘Killed His Reputation’ by Being Stupid About BTC, Says Max Keiser (#GotBitcoin?)
Blockfolio Quietly Patches Years-Old Security Hole That Exposed Source Code (#GotBitcoin?)
Bitcoin Won As Store of Value In Coronavirus Crisis — Hedge Fund CEO
Decentralized VPN Gaining Steam At 100,000 Users Worldwide (#GotBitcoin?)
Crypto Exchange Offers Credit Lines so Institutions Can Trade Now, Pay Later (#GotBitcoin?)
Zoom Develops A Cryptocurrency Paywall To Reward Creators Video Conferencing Sessions (#GotBitcoin?)
Bitcoin Startup Purse.io And Major Bitcoin Cash Partner To Shut Down After 6-Year Run
Open Interest In CME Bitcoin Futures Rises 70% As Institutions Return To Market
Square’s Users Can Route Stimulus Payments To BTC-Friendly Cash App
$1.1 Billion BTC Transaction For Only $0.68 Demonstrates Bitcoin’s Advantage Over Banks
Bitcoin Could Become Like ‘Prison Cigarettes’ Amid Deepening Financial Crisis
Bitcoin Holds Value As US Debt Reaches An Unfathomable $24 Trillion
How To Get Money (Crypto-currency) To People In An Emergency, Fast
Bitcoin Miner Manufacturers Mark Down Prices Ahead of Halving
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Bitcoin Starts Quarter With Price Down Just 10% YTD vs U.S. Stock’s Worst Quarter Since 2008
Bitcoin Enthusiasts, Liberal Lawmakers Cheer A Fed-Backed Digital Dollar
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The CFTC Just Defined What ‘Actual Delivery’ of Crypto Should Look Like (#GotBitcoin?)
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Crypto Analyst Accused of Photoshopping Trade Screenshots (#GotBitcoin?)
QE4 Begins: Fed Cuts Rates, Buys $700B In Bonds; Bitcoin Rallies 7.7%
Mike Novogratz And Andreas Antonopoulos On The Bitcoin Crash
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Fatburger And Others Feed $30 Million Into Ethereum For New Bond Offering (#GotBitcoin?)
Pornhub Will Integrate PumaPay Recurring Subscription Crypto Payments (#GotBitcoin?)
Intel SGX Vulnerability Discovered, Cryptocurrency Keys Threatened
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Countries That First Outlawed Crypto But Then Embraced It (#GotBitcoin?)
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HTC’s New 5G Router Can Host A Full Bitcoin Node
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Analyst Claims 98% of Mining Rigs Fail to Verify Transactions (#GotBitcoin?)
Blockchain Storage Offers Security, Data Transparency And immutability. Get Over it!
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Coinbase Wallet Now Allows To Send Crypto Through Usernames (#GotBitcoin)
New ‘Simpsons’ Episode Features Jim Parsons Giving A Crypto Explainer For The Masses (#GotBitcoin?)
Crypto-currency Founder Met With Warren Buffett For Charity Lunch (#GotBitcoin?)
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Coinbase Becomes Direct Visa Card Issuer With Principal Membership
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You Can Now Donate Bitcoin Or Fiat To Show Your Support For All Of Our Valuable Content
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US Deficit Will Be At Least 6 Times Bitcoin Market Cap — Every Year (#GotBitcoin?)
Central Banks Warm To Issuing Digital Currencies (#GotBitcoin?)
Meet The Crypto Angel Investor Running For Congress In Nevada (#GotBitcoin?)
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H.R.5635 – Virtual Currency Tax Fairness Act of 2020 ($200.00 Limit) 116th Congress (2019-2020)
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A Blockchain-Secured Home Security Camera Won Innovation Awards At CES 2020 Las Vegas
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Google Suspends MetaMask From Its Play App Store, Citing “Deceptive Services”
Christmas Shopping: Where To Buy With Crypto This Festive Season
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Coinbase CEO Armstrong Wins Patent For Tech Allowing Users To Email Bitcoin
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At A Refugee Camp In Iraq, A 16-Year-Old Syrian Is Teaching Crypto Basics
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The Ultimate List of Bitcoin Developments And Accomplishments
Charities Put A Bitcoin Twist On Giving Tuesday
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An Army Of Bitcoin Devs Is Battle-Testing Upgrades To Privacy And Scaling
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Max Keiser: Bitcoin’s ‘Self-Settlement’ Is A Revolution Against Dollar
Blockchain Can And Will Replace The IRS
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Jack Dorsey: You Can Buy A Fraction Of Berkshire Stock Or ‘Stack Sats’
Bitcoin Price Skyrockets $500 In Minutes As Bakkt BTC Contracts Hit Highs
Bitcoin’s Irreversibility Challenges International Private Law: Legal Scholar
Bitcoin Has Already Reached 40% Of Average Fiat Currency Lifespan
Yes, Even Bitcoin HODLers Can Lose Money In The Long-Term: Here’s How (#GotBitcoin?)
Unicef To Accept Donations In Bitcoin (#GotBitcoin?)
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Switzerland’s ‘Crypto Valley’ Is Bringing Blockchain To Zurich
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Bitcoin Developer Amir Taaki, “We Can Crash National Economies” (#GotBitcoin?)
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SEC Enters Settlement Talks With Alleged Fraudulent Firm Veritaseum (#GotBitcoin?)
Blockstream’s Samson Mow: Bitcoin’s Block Size Already ‘Too Big’
Attorneys Seek Bank Of Ireland Execs’ Testimony Against OneCoin Scammer (#GotBitcoin?)
OpenLibra Plans To Launch Permissionless Fork Of Facebook’s Stablecoin (#GotBitcoin?)
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Class Action Accuses Tether And Bitfinex Of Market Manipulation (#GotBitcoin?)
Sharia Goldbugs: How ISIS Created A Currency For World Domination (#GotBitcoin?)
Bitcoin Eyes Demand As Hong Kong Protestors Announce Bank Run (#GotBitcoin?)
How To Securely Transfer Crypto To Your Heirs
‘Gold-Backed’ Crypto Token Promoter Karatbars Investigated By Florida Regulators (#GotBitcoin?)
Crypto News From The Spanish-Speaking World (#GotBitcoin?)
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‘Gold-Backed’ Crypto Token Promoter Karatbars Investigated By Florida Regulators (#GotBitcoin?)
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[PSA] Non-genuine Trezor One Devices Spotted (#GotBitcoin?)
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Wesley Snipes Is Launching A Tokenized $25 Million Movie Fund (#GotBitcoin?)
Mystery 94K BTC Transaction Becomes Richest Non-Exchange Address (#GotBitcoin?)
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Four Out Of Five Top Bitcoin QR Code Generators Are Scams: Report (#GotBitcoin?)
Waves Platform And The Abyss To Jointly Launch Blockchain-Based Games Marketplace (#GotBitcoin?)
Bitmain Ramps Up Power And Efficiency With New Bitcoin Mining Machine (#GotBitcoin?)
Ledger Live Now Supports Over 1,250 Ethereum-Based ERC-20 Tokens (#GotBitcoin?)
Miss Finland: Bitcoin’s Risk Keeps Most Women Away From Cryptocurrency (#GotBitcoin?)
Artist Akon Loves BTC And Says, “It’s Controlled By The People” (#GotBitcoin?)
Ledger Live Now Supports Over 1,250 Ethereum-Based ERC-20 Tokens (#GotBitcoin?)
Co-Founder Of LinkedIn Presents Crypto Rap Video: Hamilton Vs. Satoshi (#GotBitcoin?)
Crypto Insurance Market To Grow, Lloyd’s Of London And Aon To Lead (#GotBitcoin?)
No ‘AltSeason’ Until Bitcoin Breaks $20K, Says Hedge Fund Manager (#GotBitcoin?)
NSA Working To Develop Quantum-Resistant Cryptocurrency: Report (#GotBitcoin?)
Custody Provider Legacy Trust Launches Crypto Pension Plan (#GotBitcoin?)
Vaneck, SolidX To Offer Limited Bitcoin ETF For Institutions Via Exemption (#GotBitcoin?)
Russell Okung: From NFL Superstar To Bitcoin Educator In 2 Years (#GotBitcoin?)
Bitcoin Miners Made $14 Billion To Date Securing The Network (#GotBitcoin?)
Why Does Amazon Want To Hire Blockchain Experts For Its Ads Division?
Argentina’s Economy Is In A Technical Default (#GotBitcoin?)
Blockchain-Based Fractional Ownership Used To Sell High-End Art (#GotBitcoin?)
Portugal Tax Authority: Bitcoin Trading And Payments Are Tax-Free (#GotBitcoin?)
Bitcoin ‘Failed Safe Haven Test’ After 7% Drop, Peter Schiff Gloats (#GotBitcoin?)
Bitcoin Dev Reveals Multisig UI Teaser For Hardware Wallets, Full Nodes (#GotBitcoin?)
Bitcoin Price: $10K Holds For Now As 50% Of CME Futures Set To Expire (#GotBitcoin?)
Bitcoin Realized Market Cap Hits $100 Billion For The First Time (#GotBitcoin?)
Stablecoins Begin To Look Beyond The Dollar (#GotBitcoin?)
Bank Of England Governor: Libra-Like Currency Could Replace US Dollar (#GotBitcoin?)
Binance Reveals ‘Venus’ — Its Own Project To Rival Facebook’s Libra (#GotBitcoin?)
The Real Benefits Of Blockchain Are Here. They’re Being Ignored (#GotBitcoin?)
CommBank Develops Blockchain Market To Boost Biodiversity (#GotBitcoin?)
SEC Approves Blockchain Tech Startup Securitize To Record Stock Transfers (#GotBitcoin?)
SegWit Creator Introduces New Language For Bitcoin Smart Contracts (#GotBitcoin?)
You Can Now Earn Bitcoin Rewards For Postmates Purchases (#GotBitcoin?)
Bitcoin Price ‘Will Struggle’ In Big Financial Crisis, Says Investor (#GotBitcoin?)
Fidelity Charitable Received Over $100M In Crypto Donations Since 2015 (#GotBitcoin?)
Would Blockchain Better Protect User Data Than FaceApp? Experts Answer (#GotBitcoin?)
Just The Existence Of Bitcoin Impacts Monetary Policy (#GotBitcoin?)
What Are The Biggest Alleged Crypto Heists And How Much Was Stolen? (#GotBitcoin?)
IRS To Cryptocurrency Owners: Come Clean, Or Else!
Coinbase Accidentally Saves Unencrypted Passwords Of 3,420 Customers (#GotBitcoin?)
Bitcoin Is A ‘Chaos Hedge, Or Schmuck Insurance‘ (#GotBitcoin?)
Bakkt Announces September 23 Launch Of Futures And Custody
Coinbase CEO: Institutions Depositing $200-400M Into Crypto Per Week (#GotBitcoin?)
Researchers Find Monero Mining Malware That Hides From Task Manager (#GotBitcoin?)
Crypto Dusting Attack Affects Nearly 300,000 Addresses (#GotBitcoin?)
A Case For Bitcoin As Recession Hedge In A Diversified Investment Portfolio (#GotBitcoin?)
SEC Guidance Gives Ammo To Lawsuit Claiming XRP Is Unregistered Security (#GotBitcoin?)
15 Countries To Develop Crypto Transaction Tracking System: Report (#GotBitcoin?)
US Department Of Commerce Offering 6-Figure Salary To Crypto Expert (#GotBitcoin?)
Mastercard Is Building A Team To Develop Crypto, Wallet Projects (#GotBitcoin?)
Canadian Bitcoin Educator Scams The Scammer And Donates Proceeds (#GotBitcoin?)
Amazon Wants To Build A Blockchain For Ads, New Job Listing Shows (#GotBitcoin?)
Shield Bitcoin Wallets From Theft Via Time Delay (#GotBitcoin?)
Blockstream Launches Bitcoin Mining Farm With Fidelity As Early Customer (#GotBitcoin?)
Commerzbank Tests Blockchain Machine To Machine Payments With Daimler (#GotBitcoin?)
Man Takes Bitcoin Miner Seller To Tribunal Over Electricity Bill And Wins (#GotBitcoin?)
Bitcoin’s Computing Power Sets Record As Over 100K New Miners Go Online (#GotBitcoin?)
Walmart Coin And Libra Perform Major Public Relations For Bitcoin (#GotBitcoin?)
Judge Says Buying Bitcoin Via Credit Card Not Necessarily A Cash Advance (#GotBitcoin?)
Poll: If You’re A Stockowner Or Crypto-Currency Holder. What Will You Do When The Recession Comes?
1 In 5 Crypto Holders Are Women, New Report Reveals (#GotBitcoin?)
Beating Bakkt, Ledgerx Is First To Launch ‘Physical’ Bitcoin Futures In Us (#GotBitcoin?)
Facebook Warns Investors That Libra Stablecoin May Never Launch (#GotBitcoin?)
Government Money Printing Is ‘Rocket Fuel’ For Bitcoin (#GotBitcoin?)
Bitcoin-Friendly Square Cash App Stock Price Up 56% In 2019 (#GotBitcoin?)
Safeway Shoppers Can Now Get Bitcoin Back As Change At 894 US Stores (#GotBitcoin?)
TD Ameritrade CEO: There’s ‘Heightened Interest Again’ With Bitcoin (#GotBitcoin?)
Venezuela Sets New Bitcoin Volume Record Thanks To 10,000,000% Inflation (#GotBitcoin?)
Newegg Adds Bitcoin Payment Option To 73 More Countries (#GotBitcoin?)
China’s Schizophrenic Relationship With Bitcoin (#GotBitcoin?)
More Companies Build Products Around Crypto Hardware Wallets (#GotBitcoin?)
Bakkt Is Scheduled To Start Testing Its Bitcoin Futures Contracts Today (#GotBitcoin?)
Bitcoin Network Now 8 Times More Powerful Than It Was At $20K Price (#GotBitcoin?)
Crypto Exchange BitMEX Under Investigation By CFTC: Bloomberg (#GotBitcoin?)
“Bitcoin An ‘Unstoppable Force,” Says US Congressman At Crypto Hearing (#GotBitcoin?)
Bitcoin Network Is Moving $3 Billion Daily, Up 210% Since April (#GotBitcoin?)
Cryptocurrency Startups Get Partial Green Light From Washington
Fundstrat’s Tom Lee: Bitcoin Pullback Is Healthy, Fewer Searches Аre Good (#GotBitcoin?)
Bitcoin Lightning Nodes Are Snatching Funds From Bad Actors (#GotBitcoin?)
The Provident Bank Now Offers Deposit Services For Crypto-Related Entities (#GotBitcoin?)
Bitcoin Could Help Stop News Censorship From Space (#GotBitcoin?)
US Sanctions On Iran Crypto Mining — Inevitable Or Impossible? (#GotBitcoin?)
US Lawmaker Reintroduces ‘Safe Harbor’ Crypto Tax Bill In Congress (#GotBitcoin?)
EU Central Bank Won’t Add Bitcoin To Reserves — Says It’s Not A Currency (#GotBitcoin?)
The Miami Dolphins Now Accept Bitcoin And Litecoin Crypt-Currency Payments (#GotBitcoin?)
Trump Bashes Bitcoin And Alt-Right Is Mad As Hell (#GotBitcoin?)
Goldman Sachs Ramps Up Development Of New Secret Crypto Project (#GotBitcoin?)
Blockchain And AI Bond, Explained (#GotBitcoin?)
Grayscale Bitcoin Trust Outperformed Indexes In First Half Of 2019 (#GotBitcoin?)
XRP Is The Worst Performing Major Crypto Of 2019 (GotBitcoin?)
Bitcoin Back Near $12K As BTC Shorters Lose $44 Million In One Morning (#GotBitcoin?)
As Deutsche Bank Axes 18K Jobs, Bitcoin Offers A ‘Plan ฿”: VanEck Exec (#GotBitcoin?)
Argentina Drives Global LocalBitcoins Volume To Highest Since November (#GotBitcoin?)
‘I Would Buy’ Bitcoin If Growth Continues — Investment Legend Mobius (#GotBitcoin?)
Lawmakers Push For New Bitcoin Rules (#GotBitcoin?)
Facebook’s Libra Is Bad For African Americans (#GotBitcoin?)
Crypto Firm Charity Announces Alliance To Support Feminine Health (#GotBitcoin?)
Canadian Startup Wants To Upgrade Millions Of ATMs To Sell Bitcoin (#GotBitcoin?)
Trump Says US ‘Should Match’ China’s Money Printing Game (#GotBitcoin?)
Casa Launches Lightning Node Mobile App For Bitcoin Newbies (#GotBitcoin?)
Bitcoin Rally Fuels Market In Crypto Derivatives (#GotBitcoin?)
World’s First Zero-Fiat ‘Bitcoin Bond’ Now Available On Bloomberg Terminal (#GotBitcoin?)
Buying Bitcoin Has Been Profitable 98.2% Of The Days Since Creation (#GotBitcoin?)
Another Crypto Exchange Receives License For Crypto Futures
From ‘Ponzi’ To ‘We’re Working On It’ — BIS Chief Reverses Stance On Crypto (#GotBitcoin?)
These Are The Cities Googling ‘Bitcoin’ As Interest Hits 17-Month High (#GotBitcoin?)
Venezuelan Explains How Bitcoin Saves His Family (#GotBitcoin?)
Quantum Computing Vs. Blockchain: Impact On Cryptography
This Fund Is Riding Bitcoin To Top (#GotBitcoin?)
Bitcoin’s Surge Leaves Smaller Digital Currencies In The Dust (#GotBitcoin?)
Bitcoin Exchange Hits $1 Trillion In Trading Volume (#GotBitcoin?)
Bitcoin Breaks $200 Billion Market Cap For The First Time In 17 Months (#GotBitcoin?)
You Can Now Make State Tax Payments In Bitcoin (#GotBitcoin?)
Religious Organizations Make Ideal Places To Mine Bitcoin (#GotBitcoin?)
Goldman Sacs And JP Morgan Chase Finally Concede To Crypto-Currencies (#GotBitcoin?)
Bitcoin Heading For Fifth Month Of Gains Despite Price Correction (#GotBitcoin?)
Breez Reveals Lightning-Powered Bitcoin Payments App For IPhone (#GotBitcoin?)
Big Four Auditing Firm PwC Releases Cryptocurrency Auditing Software (#GotBitcoin?)
Amazon-Owned Twitch Quietly Brings Back Bitcoin Payments (#GotBitcoin?)
JPMorgan Will Pilot ‘JPM Coin’ Stablecoin By End Of 2019: Report (#GotBitcoin?)
Is There A Big Short In Bitcoin? (#GotBitcoin?)
Coinbase Hit With Outage As Bitcoin Price Drops $1.8K In 15 Minutes
Samourai Wallet Releases Privacy-Enhancing CoinJoin Feature (#GotBitcoin?)
There Are Now More Than 5,000 Bitcoin ATMs Around The World (#GotBitcoin?)
You Can Now Get Bitcoin Rewards When Booking At Hotels.Com (#GotBitcoin?)
North America’s Largest Solar Bitcoin Mining Farm Coming To California (#GotBitcoin?)
Bitcoin On Track For Best Second Quarter Price Gain On Record (#GotBitcoin?)
Bitcoin Hash Rate Climbs To New Record High Boosting Network Security (#GotBitcoin?)
Bitcoin Exceeds 1Million Active Addresses While Coinbase Custodies $1.3B In Assets
Why Bitcoin’s Price Suddenly Surged Back $5K (#GotBitcoin?)
Bitcoin’s Lightning Comes To Apple Smartwatches With New App (#GotBitcoin?)
E-Trade To Offer Crypto Trading (#GotBitcoin)
Bitfinex Used Tether Reserves To Mask Missing $850 Million, Probe Finds (#GotBitcoin?)
21-Year-Old Jailed For 10 Years After Stealing $7.5M In Crypto By Hacking Cell Phones (#GotBitcoin?)
You Can Now Shop With Bitcoin On Amazon Using Lightning (#GotBitcoin?)
Afghanistan, Tunisia To Issue Sovereign Bonds In Bitcoin, Bright Future Ahead (#GotBitcoin?)
Crypto Faithful Say Blockchain Can Remake Securities Market Machinery (#GotBitcoin?)
Disney In Talks To Acquire The Owner Of Crypto Exchanges Bitstamp And Korbit (#GotBitcoin?)
Crypto Exchange Gemini Rolls Out Native Wallet Support For SegWit Bitcoin Addresses (#GotBitcoin?)
Binance Delists Bitcoin SV, CEO Calls Craig Wright A ‘Fraud’ (#GotBitcoin?)
Bitcoin Outperforms Nasdaq 100, S&P 500, Grows Whopping 37% In 2019 (#GotBitcoin?)
Bitcoin Passes A Milestone 400 Million Transactions (#GotBitcoin?)
Future Returns: Why Investors May Want To Consider Bitcoin Now (#GotBitcoin?)
Next Bitcoin Core Release To Finally Connect Hardware Wallets To Full Nodes (#GotBitcoin?)
Major Crypto-Currency Exchanges Use Lloyd’s Of London, A Registered Insurance Broker (#GotBitcoin?)
How Bitcoin Can Prevent Fraud And Chargebacks (#GotBitcoin?)
Why Bitcoin’s Price Suddenly Surged Back $5K (#GotBitcoin?)
Zebpay Becomes First Exchange To Add Lightning Payments For All Users (#GotBitcoin?)
Coinbase’s New Customer Incentive: Interest Payments, With A Crypto Twist (#GotBitcoin?)
The Best Bitcoin Debit (Cashback) Cards Of 2019 (#GotBitcoin?)
Real Estate Brokerages Now Accepting Bitcoin (#GotBitcoin?)
Ernst & Young Introduces Tax Tool For Reporting Cryptocurrencies (#GotBitcoin?)
How Will Bitcoin Behave During A Recession? (#GotBitcoin?)
Investors Run Out of Options As Bitcoin, Stocks, Bonds, Oil Cave To Recession Fears (#GotBitcoin?)
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